Consortium partners

consortium-ppl 

Universitaet Zuerich (UZH)

Universitaet Zuerich (UZH)

Further Information : http://www.unizh.ch/

Organizational Activities

The University of Zürich (UZH) enjoys international renown as a place of education and research. 2000 lecturers in 140 special institutes provide the broadest range of subjects and courses available from any Swiss seat of higher education. With 24,000 students and 1,900 graduates every year, UZH is Switzerland’s largest university. UZH’s international reputation is based on groundbreaking research, particularly in molecular biology, brain research and anthropology, and on the work of the University Hospital and Veterinary Hospital. The lab provides excellence in both diagnostic neuropathology while at the same time performing competitive science on important issues of nervous system pathologies. This is accomplished by training biological scientists as well as physician scientists, and for this reason the lab of Prof. Aguzzi is the largest “producer” of MD-PhD graduates at the University of Zurich. The Institute of Neuropathology is an integral and organic part of the Department of Pathology at the University Hospital of Zürich. As such, the lab provides an optimal interphase between basic and medical science.

Role in the Project

Key Personnel

Adriano Aguzzi, MD PhD FRCP FRCPath, is professor of Neuropathology at the University of Zurich Medical School. His research has focused on prions, exploring how they damage brain cells, how they reach the brain after entering the body, and why they accumulate in lymphatic organs (~1800 citations in 2010; H index 75). Dr. Aguzzi has also developed and patented diagnostic and therapeutic procedures for prion diseases. He is the founder and director of the Swiss National Reference Center for Prion Diseases since 1995, and has served for eight years as a member of the British Government’s Spongiform Encephalopathy Advisory Committee. He is the past president of the Swiss Society of Neuropathology, and has been Associate Dean for Research at the University of Zurich Medical School. Among other honors, he received the Gold Medal of the European Molecular Biology Organization 1998, the Ernst-Jung Award 2001, the Robert-Koch Award 2003, and the Marcel-Benoist Award 2004. He holds honorary doctorates in Medicine, Veterinary Medicine, and in Biology bestowed, respectively, by the Universities of Liege, Teramo, and Bologna.

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Jeppe Falsig Pedersen, is a post-doc at the institute of Neuropathology, co-supervising PhD and MD students. He holds a PhD since 2008 from the University of Zürich. He joined the laboratory of Professor Adriano Aguzzi in 2004 where he specialized in establishing and analysing long-term ex vivo and in vivo models of protein misfolding-diseases.

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Silvia Sorce, is a post-doc at the institute of Neuropathology. She did her PhD in the laboratory of Professor Krause at the University of Geneva, working on NOX enzymes in the central nervous system. She joined the laboratory of Professor Adriano Aguzzi in 2011 and is currently studying the involvement of NOX enzymes in animal models of protein misfolding-diseases.

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Mario Nuvolone, is a MD-PhD student at the institute of Neuropathology. He is developing new animal models of protein misfolding-diseases to be used in translational medicine.

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Despoina Goniotaki, is a PhD student at the institute of Neuropathology since October 2011, involved in the establishment of brain slice cultures of relevant transgenic mice to study protein misfolding-diseases.

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Badma Segarane, is a PhD student at the Institute of Neuropathology. She is currently establishing and analysing long-term ex vivo hippocampal culture models of tauopathies.

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