Consortium partners

consortium-ppl 

The Victor Chang Cardiac Research Institute

The Victor Chang Cardiac Research Institute

Further Information : http://www.victorchang.edu.au

Organizational Activities

The Victor Chang Cardiac Research Institute (VCCRI) has an international reputation for excellence in biomedical research. The Institute's work is supported by peer-reviewed grants from agencies such as the NHMRC, the ARC, the National Heart Foundation, the Wellcome Foundation UK and the NIH USA, as well as attracting significant philanthropic support. As one of Australia’s leading research facilities, the VCCRI has a commitment to ensuring the highest standards of research performance and training.

VCCRI will provide state-of-the-art infrastructure for research, including the Oxidative Stress Analytical Facility, a new core facility of the Institute where a majority of the work related to NEURINOX will take place. This Facility was initiated and established by Prof. Stocker, whose research focuses on the role of oxidative processes in vascular disease. The facility has established LC/MS-based methods for the identification, quantification and sub-cellular localization of reactive oxygen species, and it continues to develop new analytical methods for the quantification of oxidative stress in cells, tissues, animals and humans

Role in the Project

Key Personnel

Roland Stocker is Head of Vascular Biology and a Faculty member of the Victor Chang Cardiac Research Institute. Throughout his research career, he worked in the area of oxidative stress in health and disease, with continuous support from national and international funding agencies. He has authored 270 research publications (>18,000 citations; H index 67), and has organized several national and international conferences. Among the Awards received are the Paul Nestel Award from the Australian Atherosclerosis Society for outstanding contributions to atherosclerosis research in Australia (2007), the Lifetime Achievement Award from the Society for Free Radical Research Australasia (2010), and the Redox Pioneer Award (2011) from the journal Antioxidants Redox Signalling.

NEURINOX 

Ghassan Maghzal, PhD, Senior Post-doctoral Fellow: LC/MS-based analytics and method development. Dr Maghzal has over 10 years experience in using mass spectrometry to study redox reactions in biology, including oxidative modifications of amino acids and proteins.  His current research, funded by the Australian Research Council, involves development of LC/MS based methods for the measurement of oxidative stress, particularly superoxide and hydrogen peroxide in cells and tissues.

 NEURINOX

Magda Lam, PhD, Post-doctoral Fellow. Magda completed her PhD in the field of reactive oxygen species-induced protein oxidation at the University of Sydney. She was the Sir Zelman Cowen Universities Fund Oxidative Stress Bioanalytical Facility Officer. In this capacity she managed the facility operations, assisted in analytical method development and research projects, conducted equipment training and provided continuous support for the multi-user facility. She is now working as a post-doctoral researcher at the Victor Chang Cardiac Research Institute where she is developing new methods to detect reactive oxygen and nitrogen species of biological relevance.

 

 NEURINOX