NEURINOX publications

Note: The publications reported here below concern the NEURINOX project research activities.


Sareila O, Jaakkola N, Olofsson P, Kelkka T, Holmdahl R.

J Leukoc Biol. 2013 Mar;93(3):427-35. Epub 2012 Dec 27.

NOX Activation

Chiò A, Calvo A, Mazzini L, Cantello R, Mora G, Moglia C, Corrado L, D'Alfonso S, Majounie E, Renton A, Pisano F, Ossola I, Brunetti M, Traynor BJ, Restagno G; PARALS.

Neurology. 2012 Nov 6;79(19):1983-9. Epub 2012 Oct 24.

ALS

Pugliatti M, Parish LD, Cossu P, Leoni S, Ticca A, Saddi MV, Ortu E, Traccis S, Borghero G, Puddu R, Chiò A, Pirina P.

J Neurol. 2013 Feb;260(2):572-9. Epub 2012 Sep 30

ALS

Olsson LM, Holmdahl R.

Eur J Immunol. 2012 Aug;42(8):1969-76

Genetics

Chiò A, Mora G, Restagno G, Brunetti M, Ossola I, Barberis M, Ferrucci L, Canosa A, Manera U, Moglia C, Fuda G, Traynor BJ, Calvo A.

Neurobiol Aging. 2013 Jan;34(1):357.e1-5. Epub 2012 Aug 22.

ALS

Holmdahl R, Sareila O, Pizzolla A, Winter S, Hagert C, Jaakkola N, Kelkka T, Olsson LM, Wing K, Bäckdahl L.

Antioxid Redox Signal. 2013 Apr 20. Epub 2012 Aug 17

Models to study NOX involvement in neurodegeneration

Maghzal GJ, Krause KH, Stocker R, Jaquet V.

Free Radic Biol Med. 2012 Nov 15; 53(10):1903-18. Epub 2012 Sep 13.

NOX activity measurements

Chiò A, Battistini S, Calvo A, Caponnetto C, Conforti FL, Corbo M, Giannini F, Mandrioli J, Mora G, Sabatelli M; ITALSGEN Consortium, Ajmone C, Mastro E, Pain D, Mandich P, Penco S, Restagno G, Zollino M, Surbone A.

J Neurol Neurosurg Psychiatry. 2014 May;85(5):478-85. doi: 10.1136/jnnp-2013-305546. Epub 2013 Jul 6.

ALS

Pizzolla A, Wing K, Holmdahl R.

Am J Pathol. 2013 Oct;183(4):1144-55. doi: 10.1016/j.ajpath.2013.06.019. Epub 2013 Jul 30.

Understanding the role of NOX

T. Sonati, R. Reimann, J. Falsig, P. K. Baral, T. O’Connor, S. Hornemann, S. Yaganoglu, B. Li, U. Herrmann, B. Wieland, M. Swayampakula, M. H. Rahman, D. Das, N. Kav, R. Riek, P. Liberski, M. James & A. Aguzzi.

Nature. 2013 Sep 5;501(7465):102-6. doi: 10.1038/nature12402. Epub 2013 Jul 31.

Understanding the role of NOX

Kelkka T, Pizzolla A, Laurila JP, Friman T, Gustafsson R, Källberg E, Olsson O, Leanderson T, Rubin K, Salmi M, Jalkanen S, Holmdahl R

PLoS One. 2013 Dec 16;8(12):e84148. doi: 10.1371/journal.pone.0084148. eCollection 2013.

Models to study NOX involvement in neurodegeneration

Calvo A, Chiò A et al

Neurobiol Aging. 2012 Aug;33(8):1848.e15-20. doi: 10.1016/j.neurobiolaging.2012.02.011. Epub 2012 Mar 13

ALS

Calvo A, Moglia C, Canosa A, Brunetti M, Barberis M, Traynor BJ, Carrara G, Valentini C, Restagno G, Chiò A.

Neurobiol Aging. 2014 Jun;35(6):1513.e7-11. doi: 10.1016/j.neurobiolaging.2013.12.028. Epub 2013 Dec 27.

ALS

Hultqvist M, Olofsson P, Wallner FK, Holmdahl R

Antioxid Redox Signal. 2014 Feb 26. [Epub ahead of print]

NOX activity measurements

Mermelekas G, Makridakis M, Koeck T, Vlahou A.

Expert Rev Proteomics. 2013 Dec;10(6):537-49. doi: 10.1586/14789450.2013.855611

Ros activity measurement

Nayernia Z, Jaquet V, Krause KH.

Antioxid Redox Signal. 2014 Jun 10;20(17):2815-37. doi: 10.1089/ars.2013.5703. Epub 2014 Jan 16.

Understanding the role of NOX

Seredenina T, Demaurex N, Krause KH

Antioxid Redox Signal. 2014 Mar 17. [Epub ahead of print]

Understanding the role of NOX

Khmaladze Ia, Kelkka T, Guerard S, Wing K, Pizzolla A, Saxena A, Lundqvist K, Holmdahl M, Nandakumar KS, Holmdahl R

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3669-78. doi: 10.1073/pnas.1405798111. Epub 2014 Aug 18

Ros activity measurement

Tiago Rodrigues-Sousa, Ana Filipa Ladeirinha, Ana Raquel Santiago, Helena Carvalheiro, Bruno Raposo, Ana Alarcão, António Cabrita, Rikard Holmdahl, Lina Carvalho, M. Margarida Souto-Carneiro,

Published: May 29, 2014 - DOI: 10.1371/journal.pone.0097532

Ros activity measurement

Schauer C, Janko C, Munoz LE, Zhao Y, Kienhöfer D, Frey B, Lell M, Manger B, Rech J, Naschberger E, Holmdahl R, Krenn V, Harrer T, Jeremic I, Bilyy R, Schett G, Hoffmann M, Herrmann M1

Nat Med. 2014 May;20(5):511-7. doi: 10.1038/nm.3547. Epub 2014 Apr 28

Understanding the role of NOX

Renton AE, Chiò A, Traynor BJ

Nat Neurosci.

ALS

Asghar MN, Emani R, Alam C, Helenius TO, Grönroos TJ, Sareila O, et al.

Inflamm Bowel Dis.

Ros activity measurement

Grtiffiths HR, Bennett SJ, Olofsson P, Dunston CR

Biochemical Society Transactions

Ros activity measurement

Trocme C, Deffert C, Cachat J, Donati Y, Tissot C, Papacatzis S, et al.

J Pathol.

NOX activity measurements

Keller MF, Ferrucci L, Singleton AB, Tienari PJ, Laaksovirta H, Restagno G, Chiò A, Traynor BJ, Nalls MA.

JAMA Neurol. 2014 Sep;71(9):1123-34. doi: 10.1001/jamaneurol.2014.1184.

ALS

Lemcke S, Müller S, Möller S, Schillert A, Ziegler A, Cepok-Kauffeld S, et al.

Am J Pathol.

MS

Marrali G, Casale F, Salamone P, Fuda G, Caorsi C, Amoroso A, Brunetti M, Restagno G, Barberis M, Bertuzzo D, Canosa A, Moglia C, Calvo A, Chiò A

J. Neurol.

ALS

Rikard Holmdahl, Outi Sareila, Lina M. Olsson, Liselotte Bäckdahl and Kajsa Wing

DOI: 10.1111/imr.12378, Special Issue: Autoimmunity, Volume 269, Issue 1, pages 228–247, January 2016

Ros activity measurement

Deffert C, Schäppi MG, Pache J-C, Cachat J, Vesin D, Bisig R, et al.

PLoS Pathog. 2014 Sep 4;10(9):e1004325. doi: 10.1371/journal.ppat.1004325. eCollection 2014.

Models to study NOX involvement in neurodegeneration

Johnson JO, Glynn SM, Gibbs JR, Nalls MA, Sabatelli M, Restagno G, Drory VE, Chiò A, Rogaeva E, Traynor BJ

Brain. 2014 Dec;137(Pt 12):e311. doi: 10.1093/brain/awu265. Epub 2014 Sep 26.

ALS

Maghzal et al.

Nature. 2014 Oct 23;514(7523):E16-7. doi: 10.1038/nature13844

Inflammation

Shakya AK, Holmdahl R, Nadakumar KS, Kumar A

J Biomed Mater Res A. 2014 Oct;102(10):3409-18. doi: 10.1002/jbm.a.35013. Epub 2013 Oct 28

Ros activity measurement

Kelkka T, et al.

Antioxid Redox Signal. 2014 Dec 1;21(16):2231-45. doi: 10.1089/ars.2013.5828. Epub 2014 Jul 29

Ros activity measurement

Sorce S, Nuvolone M, Keller A, Falsig J, Varol A, Schwarz P, Bieri M, Budka H, Aguzzi A.

PLoS Pathog. 2014 Dec 11;10(12):e1004531. doi: 10.1371/journal.ppat.1004531. eCollection 2014 Dec

Understanding the role of NOX

Chio A, et al.

Neurology. 2015 Jan 20;84(3):251-8. doi: 10.1212/WNL.0000000000001159. Epub 2014 Dec 19

ALS

Chiò A, Traynor BJ

Nat Rev Neurol. 2015 Feb;11(2):72-4. doi: 10.1038/nrneurol.2014.250. Epub 2014 Dec 23

ALS

Depaulis A, Hamelin S

Rev Neurol (Paris). 2015 Mar;171(3):217-26. doi: 10.1016/j.neurol.2015.01.558. Epub 2015 Mar 4

Epilepsy

Khmaladze I. · Nandakumar K.S. · Holmdahl R.

Int Arch Allergy Immunol 2015;166:135-149 - DOI:10.1159/000375401

Ros activity measurement

Outi Sareila, Cecilia Hagert, Pia Rantakari, Matti Poutanen, Rikard Holmdahl

10.1371/journal.pone.0141974

Models to study NOX involvement in neurodegeneration

Casas Ana I., Dao V. Thao-Vi, Daiber Andreas, Maghzal Ghassan J., Di Lisa Fabio, Kaludercic Nina, Leach Sonia, Cuadrado Antonio, Jaquet Vincent, Seredenina Tamara, Krause Karl H., López Manuela G., Stocker Roland, Ghezzi Pietro, and Schmidt Harald H.H.W

Antioxidants & Redox Signaling. November 2015, 23(14): 1171-1185. doi:10.1089/ars.2015.6433.

Ros activity measurement

Dao V. Thao-Vi, Casas Ana I., Maghzal Ghassan J., Seredenina Tamara, Kaludercic Nina, Robledinos-Anton Natalia, Di Lisa Fabio, Stocker Roland, Ghezzi Pietro, Jaquet Vincent, Cuadrado Antonio, and Schmidt Harald H.H.W..

Antioxidants & Redox Signaling. November 2015, 23(14): 1113-1129. doi:10.1089/ars.2015.6430.

Ros activity measurement

Tamara Seredenina, Gianpaolo Chiriano, Aleksandra Filippova, Zeynab Nayernia, Zahia Mahiout, Laetitia Fioraso-Cartier, Olivier Plastre, Leonardo Scapozza, Karl-Heinz Krause, Vincent Jaquet

Free Radical Biology and Medicine, Volume 86, September 2015, Pages 239–249

NOX Activators

Hultqvist Malin, Olofsson Peter, Wallner Fredrik K., and Holmdahl Rikard.

Antioxidants & Redox Signaling. August 2015, 23(5): 446-459. doi:10.1089/ars.2013.5788.

Models to study NOX involvement in neurodegeneration

Bedard Karen, Whitehouse Scott, and Jaquet Vincent.

Antioxidants & Redox Signaling. August 2015, 23(5): 355-357. doi:10.1089/ars.2015.6450.

Understanding the role of NOX

Hirano Kazufumi, Chen Woei Shin, Chueng Adeline L.W., Dunne Angela A., Seredenina Tamara, Filippova Aleksandra, Ramachandran Sumitra, Bridges Angela, Chaudry Laiq, Pettman Gary, Allan Craig, Duncan Sarah, Lee Kiew Ching, Lim Jean, Ma May Thu, Ong Agnes B., Ye Nicole Y., Nasir Shabina, Mulyanidewi Sri, Aw Chiu Cheong, Oon Pamela P., Liao Shihua, Li Dizheng, Johns Douglas G., Miller Neil D., Davies Ceri H., Browne Edward R., Matsuoka Yasuji, Chen Deborah W., Jaquet Vincent, and Rutter A. Richard

Antioxidants & Redox Signaling. August 2015, 23(5): 358-374. doi:10.1089/ars.2014.6202.

NOX inhibitors

Kajsa Wing, Katrin Klocke, Annika Samuelsson and Rikard Holmdahl

European Journal of Immunology, Volume 45, Issue 5, pages 1348–1353, May 2015 - DOI: 10.1002/eji.201445020

Understanding the role of NOX

Chiò A, Traynor BJ.

Nat Rev Neurol. 2015 Feb;11(2):72-4. doi: 10.1038/nrneurol.2014.250. Epub 2014 Dec 23.

ALS

Ia Khmaladze, Amit Saxena, Kutty Selva Nandakumar and Rikard Holmdahl

European Journal of Immunology, Volume 45, Issue 8, pages 2243–2251, August 2015, DOI: 10.1002/eji.201545518

Ros activity measurement

Hamelin S, Depaulis A

Rev Neurol (Paris). 2015 Mar;171(3):227-35. doi: 10.1016/j.neurol.2015.01.560. Epub 2015 Mar 4.

Epilepsy

Adriano Chiò, MD, FAAN, Andrea Calvo, MD, PhD, Cristina Moglia, MD, Antonio Canosa, MD, Maura Brunetti, BSc, Marco Barberis, BSc, Gabriella Restagno, MD, Amelia Conte, MD, Giulia Bisogni, MD, Giuseppe Marangi, MD, Alice Moncada, MD, Serena Lattante, MD, Marcella Zollino, MD, Mario Sabatelli, MD, Alessandra Bagarotti, PhD, Lucia Corrado, PhD, Gabriele Mora, MD, Enrica Bersano, MD, Letizia Mazzini, MD, Sandra D'Alfonso, PhD; For PARALS

Published online before print January 20, 2015, doi: http:/​/​dx.​doi.​org/​10.​1212/​WNL.​0000000000001159 Neurology January 20, 2015 vol. 84 no. 3 251-258

ALS

Bitsika V, Duveau V, Simon-Areces J, Mullen W, Roucard C, Makridakis M, Mermelekas G, Savvopoulos P, Depaulis A, Vlahou A.

J Proteome Res. 2016 Apr 19. [Epub ahead of print]; PMID: 27057777 [PubMed - as supplied by publisher]

Epilepsy

Maarten A. Ligtenberg, Özcan Çınar, Rikard Holmdahl, Dimitrios Mougiakakos, Rolf Kiessling

Published: June 15, 2015

NOX Activation

Ghezzi P, Jaquet V, Marcucci F, Schmidt HH.

Br J Pharmacol

oxidative stress

Seredenina T, Nayernia Z, Sorce S, Maghzal GJ, Filippova A, Ling SC, Basset O, Plastre O, Daali Y, Rushing EJ, Giordana MT, Cleveland DW, Aguzzi A, Stocker R, Krause KH, Jaquet V.

Free Radic Biol Med. 2016 Aug;97:95-108. doi: 10.1016/j.freeradbiomed.2016.05.016. Epub 2016 May 19.

ALS

Vilhardt F, Haslund-Vinding J, Jaquet V, McBean G.

Br J Pharmacol. 2016 Jan 11

Haslund-Vinding J, McBean G, Jaquet V, Vilhardt F.

Br J Pharmacol. 2016 Jan 10

Marrali G, Salamone P, Casale F, Fuda G, Cugnasco P, Caorsi C, Amoroso A, Calvo A, Lopiano L, Cocito D, Chiò A.

Eur J Neurol. 2016 May;23(5):958-63. doi: 10.1111/ene.12971.

NOX Activation